The interesting map above shows the Great Sioux Reservation in the American west. These Native Americans were the classic buffalo hunters, living a nomadic life on the great plains hunting buffalo. They were very successful warriors and of course defeated General Custer at the battle of the Little Bighorn.
As a western tribe their contact with eastern American colonists was minimal in the early years of settlement of the United States. But their "Y" DNA is about 50% R-1 - higher than some of the eastern tribes such as the Cherokee. This is an argument against the belief that R-1 is the result of post Columbian migration and intermarriage.
http://www.ndstudies.org/resources/IndianStudies/standingrock/historical_gs_reservation.html
http://en.wikipedia.org/wiki/Y-DNA_haplogroups_in_indigenous_peoples_of_the_Americas